The continued transmission of polio virus in Pakistan and the rising numbers of polio cases since 2008 have turned into a national emergency, putting Pakistan at the risk of becoming the last remaining reservoir of endemic polio virus transmission in the world, and the only remaining threat to achieving global polio eradication. The particular strain of the Polio virus, which is specific to Pakistan, has travelled to other countries and caused outbreaks in China in 2011, and in Afghanistan (ongoing). If the situation does not improve, travel restrictions upon citizens of Pakistan endorsed by other states may be considered. While the Government has put in place reviewed plans and strategies to arrest the spread of polio, public representatives need to play a practical role to ensure they lend their support as well as oversee the success of the polio eradication initiatives in their constituencies across Pakistan. This Briefing Paper is published by PILDAT to serve as a background to MPs as well; as suggest ways and means through which MPs can support the critical polio eradication initiative.